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J Hist Neurosci. 1999 Apr;8(1):43-50.

On the discovery of Clostridium botulinum.

Author information

1
Graduate School of Neurosciences, University of Amsterdam, The Netherlands.

Abstract

A description is given of a food intoxication in 1895 at Ellezelles, a village in Belgium. As a result 3 persons died within a few days and others became seriously ill. A thorough investigation by E. van Ermengem led to the discovery of Clostridium botulinum and botulinum toxin. About 75 years later a subtype of the toxin proved to be highly effective in the treatment of dystonias and is now widely used.

PMID:
11624135
DOI:
10.1076/jhin.8.1.43.1774
[Indexed for MEDLINE]

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