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J Pediatr. 2001 Oct;139(4):593-6.

Recombinant tissue plasminogen activator in the treatment of central venous catheter occlusion in children.

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  • 1Division of Critical Care Medicine, Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

Abstract

Tissue plasminogen activator was used to treat 228 children with 320 central venous catheter (CVC) occlusion events. Patency was restored in 91% of CVCs after 1 to 3 treatments, with no adverse events. Tissue plasminogen activator is effective in restoring patency to occluded CVCs and is a viable alternative to CVC removal or urokinase treatment.

PMID:
11598611
DOI:
10.1067/mpd.2001.118195
[PubMed - indexed for MEDLINE]
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