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Curr Biol. 2001 Oct 2;11(19):R792-4.

Adhesion signaling: how beta-catenin interacts with its partners.

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Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.


The multi-functional protein beta-catenin plays essential roles in cell-cell adhesion and nuclear signaling. Elucidation of the structures of beta-catenin complexes is beginning to clarify how beta-catenin uses the same surface to bind its various partners, and provides insights into how these interactions might be regulated.

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