Format

Send to

Choose Destination
Curr Biol. 2001 Oct 2;11(19):R788-91.

Synaptic plasticity: a molecular memory switch.

Author information

1
Department of Biology and Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts 02453, USA.

Abstract

Recent work shows that two molecules with major roles in synaptic plasticity--CaMKII and the NMDA receptor--bind to each other. This binding activates CaMKII and triggers its autophosphorylation. In this state, it may act as a memory switch and strengthen synapses through enzymatic and structural processes.

PMID:
11591339
DOI:
10.1016/s0960-9822(01)00472-9
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center