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Trends Biochem Sci. 2001 Oct;26(10):582-4.

CHASE: an extracellular sensing domain common to transmembrane receptors from prokaryotes, lower eukaryotes and plants.

Author information

1
School of Biology, Georgia Institute of Technology, Atlanta, GA 30332-0230, USA.

Abstract

A novel extracellular ligand-binding domain, termed CHASE, is described in sensory adenylyl and diguanylate cyclases, and histidine kinases, in several bacterial species, Dictyostelium and plants. The CHASE domain is predicted to sense stimuli that are specific for the developmental program of an organism.

PMID:
11590001
DOI:
10.1016/s0968-0004(01)01969-7
[Indexed for MEDLINE]

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