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Clin Infect Dis. 2001 Nov 1;33(9):1536-44. Epub 2001 Oct 4.

Coccidioidomycosis in solid organ transplantation.

Author information

1
Division of Infectious Diseases, Mayo Clinic, Scottsdale, AZ 85259, USA. blair.janis@mayo.edu

Abstract

Coccidioidomycosis is an endemic fungal infection of the southwestern United States. Normally a self-limited infection in healthy hosts, coccidioidomycosis can become a serious complication in patients who have had solid organ transplantation. Among patients whose solid organ transplantation was complicated by coccidioidomycosis, the infection has a variety of clinical presentations. Disseminated disease is common and has substantial morbidity. Patients at risk for coccidioidal infection should be identified so that antifungal prophylactic therapy can be initiated. Treatment options include amphotericin B or azoles. Secondary prophylaxis is recommended because relapse is frequent.

PMID:
11588699
DOI:
10.1086/323463
[Indexed for MEDLINE]

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