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Nat Genet. 2001 Oct;29(2):109-11.

Islands of linkage disequilibrium.

Abstract

A detailed knowledge of patterns of linkage disequilibrium in human populations is widely seen as a prerequisite for effective population-based disease gene mapping. New data suggest that linkage disequilibrium is highly structured into discrete blocks of sequence separated by hot spots of recombination.

PMID:
11586289
DOI:
10.1038/ng1001-109
[Indexed for MEDLINE]

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