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Nat Rev Mol Cell Biol. 2001 Oct;2(10):769-76.

The renaissance of GSK3.

Author information

1
MRC Protein Phosphorylation Unit and Division of Signal Transduction Therapy, School of Life Sciences, University of Dundee, DD1 5EH, Scotland, UK. p.cohen@dundee.ac.uk

Abstract

Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.

PMID:
11584304
DOI:
10.1038/35096075
[Indexed for MEDLINE]
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