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J Antimicrob Chemother. 2001 Oct;48(4):583-6.

Treatment of Absidia corymbifera infection in mice with amphotericin B and itraconazole.

Author information

1
School of Medicine, Section of Infectious Diseases, University of Manchester, Hope Hospital, Salford, Manchester M6 8HD, UK.

Abstract

The activities of amphotericin B and itraconazole were studied in a temporarily neutropenic murine model of disseminated Absidia corymbifera infection, caused by two different strains. Amphotericin B MICs were 0.25 mg/L for both strains and itraconazole MICs were 1 and 2 mg/L. Amphotericin B was effective in vivo with both isolates. Itraconazole was less effective.

PMID:
11581243
DOI:
10.1093/jac/48.4.583
[Indexed for MEDLINE]

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