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Neuron. 2001 Sep 27;31(6):876-7.

Eph receptors tingle the spine.

Author information

1
Center for Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Abstract

During the development of excitatory synapses, molecules cluster on dendrites to form postsynaptic densities, and specialized structures known as spines appear. EphB2 is demonstrated to control this process by associating with and phosphorylating a key postsynaptic molecule, syndecan-2, thereby initiating the maturation of dendritic spines.

PMID:
11580887
DOI:
10.1016/s0896-6273(01)00441-x
[Indexed for MEDLINE]
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