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Behav Res Ther. 2001 Oct;39(10):1151-62.

Two strategies to increase adherence to HIV antiretroviral medication: life-steps and medication monitoring.

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1
Massachusetts General Hospital and Harvard Medical School, Boston MA 02114, USA.

Abstract

Advances in the medical treatment of HIV have made it clear that adherence to highly active antiretroviral treatment is a crucial feature for treatment success. The present paper had two goals: (1) to examine psychosocial predictors of adherence in persons receiving HIV antiretroviral therapy; (2) to compared two minimal-treatment interventions to increase HIV medication adherence in a subset of persons who self-reported less than perfect adherence. One of the interventions, Life-Steps, is a single-session intervention utilizing cognitive-behavioral, motivational interviewing, and problem-solving techniques. The other intervention, self-monitoring, utilizes a pill-diary and an adherence questionnaire alone. Significant correlates of adherence included depression, social support, adherence self-efficacy, and punishment beliefs about HIV. Depression was a significant unique predictor of adherence over and above the other variables. Both interventions yielded improvement in adherence from baseline, and the Life-Steps intervention showed faster improvements in adherence for persons with extant adherence problems.

PMID:
11579986
DOI:
10.1016/s0005-7967(00)00091-7
[Indexed for MEDLINE]

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