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Clin Infect Dis. 2001 Nov 1;33(9):e109-11. Epub 2001 Sep 26.

Cerebrospinal fluid penetration of levofloxacin in patients with spontaneous acute bacterial meningitis.

Author information

1
Department of Infectious Diseases, Regional Hospital Cà Foncello, Treviso, Italy. pscotton@ulss.tv.it

Abstract

We have assessed levofloxacin penetration in cerebrospinal fluid (CSF) and the liquor-to-plasma ratio (C(L)/C(P)) at 2 hours after dosing in 5 patients with spontaneous acute bacterial meningitis. CSF levofloxacin concentration at 2 hours after dosing was 1.99+/-0.67 microg/mL, and the C(L)/C(P) at 2 hours after dosing was 0.34+/-0.09.

PMID:
11577376
DOI:
10.1086/323406
[Indexed for MEDLINE]

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