Format

Send to

Choose Destination
Rapid Commun Mass Spectrom. 2001;15(19):1849-54.

Improved low-energy electron injection systems for high rate electron capture dissociation in Fourier transform ion cyclotron resonance mass spectrometry.

Author information

1
Ion Physics Division, Angström Laboratory, Uppsala University, Box 534, SE-751 21 Uppsala, Sweden.

Abstract

New low-energy electron injection systems based on indirectly heated dispenser cathodes facilitate electron capture dissociation (ECD) in Fourier transform ion cyclotron resonance (FTICR) mass spectrometry. In this joint report, details are presented of the design and performance of these systems on two commercial FTICR instruments, 9.4 T Bruker BioAPEX in Uppsala and 4.7 T IonSpec Ultima in Odense. New results include obtaining meaningful one-scan MS/MS data for isolated precursor ions with millisecond irradiation times. The ECD rate improvement is not only due to the larger total electron current, but the larger emitting area as well.

PMID:
11565103
DOI:
10.1002/rcm.448
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center