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Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):11845-6. Epub 2001 Sep 18.

Mechanisms of pain.

Author information

1
Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA. cstucky@mcw.edu

Abstract

Persistent or chronic pain is the primary reason people seek medical care, yet current therapies are either inadequate for certain types of pain or cause intolerable side effects. Recently, pain neurobiologists have identified a number of cellular and molecular processes that lead to the initiation and maintenance of pain. Understanding these underlying mechanisms has given significant promise for the development of more effective, more specific pain therapies in the near future.

PMID:
11562504
PMCID:
PMC59728
DOI:
10.1073/pnas.211373398
[Indexed for MEDLINE]
Free PMC Article

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