Utilization of prebiotic carbohydrates by yeasts of therapeutic relevance

Lett Appl Microbiol. 2001 Oct;33(4):251-5. doi: 10.1046/j.1472-765x.2001.00991.x.

Abstract

Aims: To investigate 17 strains of therapeutically relevant strains of Saccharomyces cerevisiae (including 10 strains of so-called S. boulardii) isolated from various pharmaceutical products, feed supplements and brewer's yeast for their capability of utilizing selected carbohydrates of prebiotic importance.

Methods and results: Automated turbidimetric measurements and conventional test combinations were used to examine the basic sugar assimilation profiles of the test strains. It was shown that none of the so-called S. boulardii strains utilized galactose and palatinose. Among the prebiotic substrates, the yeasts indicated a pronounced preference for metabolizing the fructo-oligosaccharides.

Conclusion: Yeast strains of therapeutic relevance can be successfully combined with certain prebiotics in symbiotic formulations.

Significance and impact of the study: The results of this study may serve as a basis for the development of new pharmaceutical preparations for medical therapy and a better understanding of intestinal micro-ecology.

MeSH terms

  • Carbohydrate Metabolism*
  • Intestines / microbiology
  • Nephelometry and Turbidimetry
  • Saccharomyces cerevisiae / classification
  • Saccharomyces cerevisiae / growth & development
  • Saccharomyces cerevisiae / metabolism*