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Nature. 2001 Sep 13;413(6852):128-9.

Nitrogen fixation. Endocrine disrupters and flavonoid signalling.

Author information

1
Environmental Endocrinology Laboratory, Center for Bioenvironmental Research at Tulane and Xavier Universities, New Orleans, Louisiana 70112, USA.

Abstract

Nitrogen fixation is a symbiotic process initiated by chemical signals from legumes that are recognized by soil bacteria. Here we show that some endocrine-disrupting chemicals (EDCs), so called because of their effect on hormone-signalling pathways in animal cells, also interfere with the symbiotic signalling that leads to nitrogen fixation. Our results raise the possibility that these phytochemically activated pathways may have features in common with hormonal signalling in vertebrates, thereby extending the biological and ecological impact of EDCs.

PMID:
11557969
DOI:
10.1038/35093163
[Indexed for MEDLINE]

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