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Antimicrob Agents Chemother. 2001 Oct;45(10):2897-901.

Antimalarial drugs clear resistant parasites from partially immune hosts.

Author information

  • 1Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Rd., Edinburgh EH9 3JT, United Kingdom.

Abstract

Circumstantial evidence in human malaria suggests that elimination of parasites by drug treatment meets higher success rates in individuals having some background immunity. In this study, using the rodent malaria model Plasmodium chabaudi, we show that drug-resistant parasites can be cleared by drugs when the host is partially immune.

PMID:
11557487
PMCID:
PMC90749
DOI:
10.1128/AAC.45.10.2897-2901.2001
[PubMed - indexed for MEDLINE]
Free PMC Article
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