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J Bacteriol. 2001 Oct;183(19):5747-50.

The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth.

Author information

1
Département de Biochimie Médicale, Centre Médical Universitaire, Université de Genève, 1211 Genève 4, Switzerland. pierre.genevaux@medecine.unige.ch

Abstract

The DnaK chaperone of Escherichia coli is known to interact with the J domains of DnaJ, CbpA, and DjlA. By constructing multiple mutants, we found that the djlA gene was essential for bacterial growth above 37 degrees C in the absence of dnaJ. This essentiality depended upon the J domain of DjlA but not upon the normal membrane location of DjlA.

PMID:
11544239
PMCID:
PMC95468
DOI:
10.1128/JB.183.19.5747-5750.2001
[Indexed for MEDLINE]
Free PMC Article

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