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Curr Opin Cell Biol. 2001 Oct;13(5):563-8.

Adhesion events in angiogenesis.

Author information

1
The Scripps Research Institute, IMM-24, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Abstract

Recent work from several laboratories indicates that the coordination of endothelial cell adhesion events with growth factor receptor inputs regulates endothelial cell responses during angiogenesis. Analyses of the signaling pathways downstream of integrins, cadherins and growth-factor receptors are providing an insight into the molecular basis of known anti-angiogenic strategies, as well as into the design of novel therapies.

PMID:
11544024
DOI:
10.1016/s0955-0674(00)00252-0
[Indexed for MEDLINE]

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