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Clin Neurol Neurosurg. 2001 Oct;103(3):175-7.

Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions.

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Department of Transmissible Diseases, Instituto Nacional de Ciencias Neurológicas, Jr. Ancash 1271, Barrios Altos, 1, Lima, Peru.


A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation. Resolution of lesions in computed tomography (CT) was observed in all five patients with a single cyst, whereas all cysts survived in three patients with multiple brain parasites. One-day praziquantel is a good regimen for patients with a single viable brain cysticercus but is poorly effective for multiple cysts.

[Indexed for MEDLINE]

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