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Genome Biol. 2001;2(8):REVIEWS1023. Epub 2001 Aug 3.

The genome of Mycobacterium leprae: a minimal mycobacterial gene set.

Author information

1
Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA. Varalakshmi.Vissa@colostate.edu

Abstract

Comparison of the recently sequenced genome of the leprosy-causing pathogen Mycobacterium leprae with other mycobacterial genomes reveals a drastic gene reduction and decay in M. leprae affecting many metabolic areas, exemplified by the retention of a minimal set of genes required for cell-wall biosynthesis.

PMID:
11532219
PMCID:
PMC138955
DOI:
10.1186/gb-2001-2-8-reviews1023
[Indexed for MEDLINE]
Free PMC Article

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