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Int J Hematol. 2001 Jul;74(1):9-17.

Regulation of hematopoiesis by chemokine family members.

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  • 1Department of Microbiology and Immunology, Indiana University School of Medicine and the Walther Cancer Institute, Indianapolis 46202-5254, USA.


Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells.

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