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Appl Environ Microbiol. 2001 Sep;67(9):4374-6.

Quantitative comparisons of 16S rRNA gene sequence libraries from environmental samples.

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1
Department of Microbiology, University of Georgia, Athens, Georgia 30602-2605, USA.

Abstract

To determine the significance of differences between clonal libraries of environmental rRNA gene sequences, differences between homologous coverage curves, CX(D), and heterologous coverage curves, CXY(D), were calculated by a Cramér-von Mises-type statistic and compared by a Monte Carlo test procedure. This method successfully distinguished rRNA gene sequence libraries from soil and bioreactors and correctly failed to find differences between libraries of the same composition.

PMID:
11526051
PMCID:
PMC93175
[Indexed for MEDLINE]
Free PMC Article
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