Wingless signalling: more about the Wingless morphogen

Curr Biol. 2001 Aug 21;11(16):R638-9. doi: 10.1016/s0960-9822(01)00380-3.

Abstract

Recent work on pattern formation in the Drosophila embryo reveals a new mechanism which shapes the gradient of the secreted morphogen, Wingless: Wingless protein is degraded more rapidly on one side of its source than on the other.

MeSH terms

  • Animals
  • Drosophila Proteins*
  • Drosophila melanogaster / cytology
  • Drosophila melanogaster / embryology*
  • Drosophila melanogaster / genetics
  • Epidermal Growth Factor / metabolism
  • Morphogenesis / physiology
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins / metabolism*
  • Wnt1 Protein

Substances

  • Drosophila Proteins
  • Proto-Oncogene Proteins
  • Wnt1 Protein
  • wg protein, Drosophila
  • Epidermal Growth Factor