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Clin Infect Dis. 2001 Sep 15;33 Suppl 3:S124-9.

Antibiotic resistance: consequences of inaction.

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1
Center for Adaptation Genetics and Drug Resistance, Tufts University School of Medicine, Boston, MA 02111, USA. stuart.levy@tufts.edu

Abstract

Bacterial resistance presents therapeutic dilemmas to clinicians worldwide. The warnings were there long ago, but too few people heeded them. Thus an emerging problem has grown to a crisis. Resistance is an ecological phenomenon stemming from the response of bacteria to the widespread use of antibiotics and their presence in the environment. While determining the consequences of inaction on the present and future public health, we must work to remedy the lack of action in the past. By improving antibiotic use and decreasing resistance gene frequency at the local levels, we can move towards reversing the resistance problem globally.

PMID:
11524708
DOI:
10.1086/321837
[Indexed for MEDLINE]
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