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Mech Dev. 2001 Sep;107(1-2):191-4.

Differential gene expression of Xenopus Pitx1, Pitx2b and Pitx2c during cement gland, stomodeum and pituitary development.

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Forschungszentrum Karlsruhe, Institute of Toxicology and Genetics, P.O. Box 3640, D-76021 Karlsruhe, Germany.


The members of the Pitx family of homeobox transcription factors have been involved in many aspects of vertebrate embryogenesis, like for example, development of teeth, eyes and limbs. We previously reported expression patterns and function of Pitx2c in the generation of laterality and asymmetric morphogenesis of heart and gastro-intestinal tract in mouse, frog and zebrafish (Development 126 (1999) 1225; Mech. Dev. 90 (2000) 41). Here we describe the differential expression of Pitx1, Pitx2b and Pitx2c during anterior ectodermal pattern formation and differentiation of cement gland, stomodeum and pituitary in the frog Xenopus laevis.

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