Abstract
The MeOH extract of an Indonesia Eudistoma sp. ascidian contained 1,3,O(7)-trimethylisoxanthopterin (1), a novel pteridine. The purification of 1 was achieved through flash C(18) chromatography and cyano HPLC. The structure was determined primarily through the use of (1)H-(13)C and (1)H-(15)N HMBC measurements and comparison with data obtained for 1,3,7-trimethylguanine (2).
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Chromatography, High Pressure Liquid
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Gas Chromatography-Mass Spectrometry
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Guanine / analogs & derivatives
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Guanine / chemistry
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Guanine / isolation & purification*
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Guanine / pharmacology
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Indonesia
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Pterins / chemistry
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Pterins / isolation & purification*
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Pterins / pharmacology
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Spectrophotometry, Ultraviolet
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Spectroscopy, Fourier Transform Infrared
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Urochordata / chemistry*
Substances
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1,3,7-trimethylguanine
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1,3,O(7)-trimethylisoxanthopterin
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Pterins
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Guanine