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J Am Assoc Gynecol Laparosc. 2001 Aug;8(3):398-401.

Hysteroscopic findings in 344 women with recurrent spontaneous abortion.

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1
Department of Obstetrics and Gynaecology, University of Rome Tor Vergata, Ospedale San Giovanni Calibita Fatebenefratelli-Isola Tiberina, 00186 Rome, Italy.

Abstract

STUDY OBJECTIVE:

To evaluate the prevalence of different anatomic factors in women with recurrent spontaneous abortion (RSA).

DESIGN:

Retrospective analysis over 9 years (Canadian Task Force classification II-2).

SETTING:

University hospital-affiliated endoscopic unit.

PATIENTS:

Three hundred forty-four consecutive patients with RSA and 922 controls referred for abnormal uterine bleeding.

INTERVENTION:

Diagnostic hysteroscopy.

MEASUREMENTS AND MAIN RESULTS:

Major and minor uterine mullerian abnormalities (septate, unicornuate uteri) were found significantly more often in women with RSA than in controls (32% vs 6%, p <0.001). The frequency of acquired uterine anomalies (submucous myomas, polyps) was significantly higher in controls (32% vs 9%, p <0.001). No significant differences were observed between groups in frequency of adhesions (4% vs 2%).

CONCLUSION:

Major mullerian uterine abnormalities are associated with RSA, and minor uterine anomalies may be correlated with an increased risk of recurrent miscarriage.

PMID:
11509781
[Indexed for MEDLINE]
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