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Curr Biol. 2001 Jul 24;11(14):R569-72.

Cadherin function: breaking the barrier.

Author information

1
Departments of Pathology and Dermatology, Northwestern University Medical School, 303 E. Chicago Avenue, Chicago, Illinois 60611, USA.

Abstract

Three desmoglein isoforms collaborate with desmocollins to build the adhesive core of desmosomes. A recent study has shown that altering the ratio of desmoglein isoforms influences epidermal barrier function, suggesting distinct roles for these cadherins that extend beyond adhesion.

PMID:
11509257
DOI:
10.1016/s0960-9822(01)00346-3
[Indexed for MEDLINE]
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