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Neurology. 2001 Aug 14;57(3):551-3.

Delirium from nicotine withdrawal in neuro-ICU patients.

Author information

1
Division of Critical Care Neurology, Department of Neurology, Columbia-Presbyterian Medical Center and College of Physicians and Surgeons of Columbia University, New York, NY, USA. sam14@columbia.edu

Abstract

Five cases of presumed nicotine withdrawal delirium among brain-injured patients treated in a neurologic intensive care unit are presented. Each patient had a history of heavy tobacco use and experienced dramatic and sustained clinical improvement within hours of transdermal nicotine replacement. These preliminary observations suggest that nicotine withdrawal may be an under-recognized cause of delirium in patients with acute brain injury.

PMID:
11502936
[Indexed for MEDLINE]

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