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J Periodontol. 2001 Jul;72(7):953-7.

Erythema multiforme secondary to herpes simplex infection: a case report.

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  • 1Department of Dental Specialties, Mayo Clinic, Rochester, MN 55905, USA.

Abstract

BACKGROUND:

Erythema multiforme (EM) is a complex disease that may have cutaneous and/or mucosal involvement. The severity may range from mild to severe and potentially life threatening. The literature cites many factors including viruses, infections, and medications as causes. This report documents a patient who developed EM secondary to a herpes simplex viral (HSV) infection.

METHODS:

Two weeks following an eruption of herpes labialis, a 20-year-old white female patient developed acutely painful oral and labial ulcers accompanied by target skin lesions. A diagnosis of erythema multiforme (EM) was made. The patient was treated with antivirals, analgesics, and symptomatic therapy.

RESULTS:

Nine days after the onset of symptoms, the oral and cutaneous lesions had started to heal and the patient no longer required pain medication.

CONCLUSIONS:

Although the etiology of EM is still often unknown, infections with herpes simplex virus have been implicated as a possible precipitating factor. This case illustrates the association of the occurrence of EM with an HSV infection.

PMID:
11495145
DOI:
10.1902/jop.2001.72.7.953
[PubMed - indexed for MEDLINE]
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