Format

Send to

Choose Destination
See comment in PubMed Commons below
Can Fam Physician. 2001 Jul;47:1385, 1387.

Maternal obesity and risk of neural tube defects.

Author information

1
Hospital for Sick Children, Toronto, Ont.

Abstract

QUESTION:

One of my patients is taking olanzapine for schizophrenia. She has gained a lot of weight, which, I understand, often happens with some of the new atypical antipsychotics. Due to her weight gain, she failed to notice she had become pregnant. Is she at risk?

ANSWER:

Experience with olanzapine is relatively slight, but available prospective data do not show increased teratogenic risk. Adiposity, on the other hand, is associated with increased risk of neural tube defects. Only some of this risk can be reduced by folate supplementation.

PMID:
11494923
PMCID:
PMC2018535
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center