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Planta Med. 2001 Jul;67(5):443-6.

Cytotoxic activity of moronic acid and identification of the new triterpene 3,4-seco-olean-18-ene-3,28-dioic acid from Phoradendron reichenbachianum.

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1
Centro de Investigaciones Químicas de la Universidad Autónoma del Estado de Morelos, Cuernavaca, Mexico. yrios@iqunam.iquimica.unam.mx

Abstract

The cytotoxic compound moronic acid (1) and the new tetracyclic triterpene 3,4-seco-olean-18-ene-3,28-dioic acid (2), were isolated from the aerial parts of the medicinal plant Phoradendron reichenbachianum (mistletoe, Loranthaceae) through a bioassay-guided fractionation. In addition, squalene, glycerol trilinoleate, morolic acid, betulonaldehyde, betulinaldehyde, alpha-germanicol, lupeol, beta-sitosterol and beta-sitosteril glucopyranoside, were identified in this plant species. The structures were elucidated on the basis of chemical and spectroscopic evidence.

PMID:
11488459
DOI:
10.1055/s-2001-15823
[Indexed for MEDLINE]
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