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Arch Surg. 2001 Aug;136(8):864-9.

Safety and efficacy of radiofrequency thermal ablation in advanced liver tumors.

Author information

1
Department of Surgery, University of Hawaii School of Medicine, Honolulu, HI, USA.

Abstract

HYPOTHESIS:

Radiofrequency thermal ablation (RFA) can be performed safely and effectively to control local disease in patients with advanced, unresectable liver tumors.

DESIGN, SETTING, AND PATIENTS:

Prospective study of 76 patients with unresectable liver tumors who underwent RFA at a private tertiary referral hospital.

INTERVENTIONS:

Ninety-nine RFA operations were performed to ablate 328 tumors.

MAIN OUTCOME MEASURES:

Complications and local recurrence.

RESULTS:

There was 1 death (1%), major complications occurred in 7 operations (7%), and minor complications occurred in 10 operations (10%). Local recurrence was identified in 30 tumors (9%) at a mean follow-up of 15 months. Size (P<.001), vascular invasion (P<.001), and total volume ablated (P<.001) were associated with recurrence but the number of tumors was not (P =.39).

CONCLUSION:

Radiofrequency thermal ablation provides local control of advanced liver tumors with low recurrence and acceptable morbidity.

PMID:
11485520
DOI:
10.1001/archsurg.136.8.864
[Indexed for MEDLINE]

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