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Br J Pharmacol. 1975 Apr;53(4):598-9.

Effect of tetramethylenedisulphotetramine on the membrane conductance increase produced by gamma-amino-butyric acid at the crab neuromuscular junction.

Abstract

The effect of tetramethylenedisulphotetramine (TETS) on the increase in membrane conductance produced by gamma-aminobutyric acid (GABA) at the hermit crab neuromuscular junction was investigated. TETS produced a dose-dependent antagonism of GABA, which was characterized by a non-parallel shift of the log dose-conductance curve for GABA with a reduced maximal conductance change.

PMID:
1148503
PMCID:
PMC1666319
[Indexed for MEDLINE]
Free PMC Article

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