Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Rev Mol Cell Biol. 2001 Aug;2(8):589-98.

Four deaths and a funeral: from caspases to alternative mechanisms.

Author information

1
H. Lundbeck A/S, Ottiliavej 9, DK-2500 Copenhagen-Valby, Denmark. male@lundbeck.dk

Abstract

A single family of proteases, the caspases, has long been considered the pivotal executioner of all programmed cell death. However, recent findings of evolutionarily conserved, caspase-independent controlled death mechanisms have opened new perspectives on the biology of cell demise, with particular implications for neurobiology, cancer research and immunological processes.

PMID:
11483992
DOI:
10.1038/35085008
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Support Center