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Rinsho Shinkeigaku. 2001 Feb-Mar;41(2-3):154-6.

[MRI finding of CNS cryptococcosis in an HIV-positive patient].

[Article in Japanese]

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Cerebrovascular Center, Ebina East General Hospital.


We report an HIV-positive patient with CNS cryptococcosis, diagnosis of which was based on detection of Cryptococcus neoformans by Indian ink staining and culture of CSF. MRI displayed dilated Virchow-Robin space in bilateral basal ganglia which were hypointense on T1-weighted images, hyperintense on T2-weighted images, and enhanced by gadolinium administration. In addition cryptococcoma in the cerebellum was observed by MRI. This finding may suggest a progression from cryptococcal meningitis to intraparenchymal invasion, accompanied with breakdown of the blood brain barrier.

[Indexed for MEDLINE]

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