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Montelukast in 2- to 5-year-old children with asthma.

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1
Department of Allergy and Immunology, Children's Hospital of Pittsburgh, 3705 Fifth Ave., 4B 320, Pittsburgh, PA 15213, USA. skonerd@chplink.chp.edu

Abstract

Pediatric dose selection for montelukast in 2-5-year-old children was based on a pharmacokinetic approach that was also used in previously selecting a once-daily 5-mg chewable tablet for asthmatic children 6-14 years of age. A 4-mg chewable tablet administered once daily was determined to be the correct dose and was subsequently found to be safe and effective in asthmatic children 2-5 years of age.

PMID:
11475172
[Indexed for MEDLINE]
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