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Br J Dermatol. 2001 Jul;145(1):105-9.

Nodular localized primary cutaneous amyloidosis: a long-term follow-up study.

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St John's Institute of Dermatology, The Guy's, King's College and St Thomas' Medical and Dental Schools, University of London, UK.


We present long-term follow-up data on patients with nodular localized primary cutaneous amyloidosis (NLPCA) seen at the St John's Institute of Dermatology between 1968 and 1999. This is the largest clinical follow-up study of this type of amyloid to date. Based on these cases we estimate the rate of progression of NLPCA to systemic amyloidosis to be only 7%, much lower than the 50% rate currently quoted in the literature.

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