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Eur J Clin Microbiol Infect Dis. 2001 May;20(5):354-7.

Evidence of increased risk for leishmania infantum infection among HIV-seronegative intravenous drug users from southern Spain.

Author information

1
Servicio de Medicina Interna, Hospital Universitario Virgen de Valme, Seville, Spain. japineda@nacom.es

Abstract

To assess the prevalence of markers of Leishmania infection, 93 intravenous drug users and 77 nonusers of intravenous drugs underwent a Leishmania skin test and a serum Leishmania antibody search. All participants were human immunodeficiency virus seronegative. The Leishmania skin test was positive in 24 intravenous drug users and in 10 non-users of intravenous drugs (P=0.038). Leishmania seropositivity was detected in 3 of 11 active intravenous drug users and in 3 of 82 former drug injectors (P=0.02). Positivity in the Leishmania skin test was associated with intravenous drug use (adjusted odds ratio, 2.33; 95% confidence interval, 1.03-5.24). The prevalence of Leishmania infection markers among intravenous drug users is higher than that among controls. This suggests that this parasite spreads through the sharing of needles.

PMID:
11453599
[Indexed for MEDLINE]

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