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Eur J Clin Microbiol Infect Dis. 2001 May;20(5):354-7.

Evidence of increased risk for leishmania infantum infection among HIV-seronegative intravenous drug users from southern Spain.

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Servicio de Medicina Interna, Hospital Universitario Virgen de Valme, Seville, Spain.


To assess the prevalence of markers of Leishmania infection, 93 intravenous drug users and 77 nonusers of intravenous drugs underwent a Leishmania skin test and a serum Leishmania antibody search. All participants were human immunodeficiency virus seronegative. The Leishmania skin test was positive in 24 intravenous drug users and in 10 non-users of intravenous drugs (P=0.038). Leishmania seropositivity was detected in 3 of 11 active intravenous drug users and in 3 of 82 former drug injectors (P=0.02). Positivity in the Leishmania skin test was associated with intravenous drug use (adjusted odds ratio, 2.33; 95% confidence interval, 1.03-5.24). The prevalence of Leishmania infection markers among intravenous drug users is higher than that among controls. This suggests that this parasite spreads through the sharing of needles.

[Indexed for MEDLINE]

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