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Curr Opin Genet Dev. 2001 Aug;11(4):393-404.

Axis formation and patterning in zebrafish.

Author information

1
Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, New York 10016, New York, USA. schier@saturn.med.nyu.edu

Abstract

A large collection of mutations affecting zebrafish embryogenesis was described in 1996. The cloning of the affected genes has now provided novel insights into the role and regulation of signaling by BMP, Nodal, Wnt, FGF, Hedgehog, Delta, Slit, retinoic acid and lipids. Detailed analyses have revealed a complex genetic network that patterns the early embryo.

PMID:
11448625
DOI:
10.1016/s0959-437x(00)00209-4
[Indexed for MEDLINE]

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