Format

Send to

Choose Destination
Virology. 2001 Jul 20;286(1):113-8.

Reverse genetics and recombination in Phi8, a dsRNA bacteriophage.

Author information

1
Department of Microbiology, Public Health Research Institute, New York, New York 10016, USA.

Abstract

Bacteriophage Phi8 has a genome of three dsRNA segments. It is able to acquire plasmid transcripts of cDNA copies of the genomic segments as replacements of its resident chromosomes. It is also able to effect recombination between the plasmid transcripts and the resident chromosomes. Depending upon the extent of sequence identity between the plasmid transcript and the resident chromosome, the recombination can be homologous or heterologous. Homologous recombination has not previously been reported for viruses with double-stranded RNA genomes.

PMID:
11448164
DOI:
10.1006/viro.2001.0995
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center