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Magn Reson Med. 2001 Jul;46(1):1-5.

Parahydrogen-induced polarization in imaging: subsecond (13)C angiography.

Author information

1
Nycomed Innovation AB, MEDEON, SE-205 12 Malmö, Sweden. Klaes.Golman@nycomedinnovation.se

Abstract

High nuclear spin polarization of (13)C was reached in organic molecules. Enhancements of up to 10(4), compared to thermal polarization at 1.5 T, were achieved using the parahydrogen-induced polarization technique in combination with a field cycling method. While parahydrogen has no net polarization, it has a high spin order, which is retained when hydrogen is incorporated into another molecule by a chemical reaction. By subjecting this molecule to a sudden change of the external magnetic field, the spin order is transferred into net polarization. A (13)C angiogram of an animal was generated in less than a second. Magn Reson Med 46:1-5, 2001.

PMID:
11443703
[Indexed for MEDLINE]
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