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News Physiol Sci. 2001 Jun;16:114-8.

Molecular physiology of renal p-aminohippurate secretion.

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1
Zentrum Physiologie und Pathophysiologie, Georg-August-Universität, 37073 Göttingen, Germany.

Abstract

Renal proximal tubules secrete various organic anions, including drugs and p-aminohippurate (PAH). Uptake of PAH from blood into tubule cells occurs by exchange with intracellular alpha-ketoglutarate and is mediated by the organic anion transporter 1. PAH exit into tubule lumen is species specific and may involve ATP-independent and -dependent transporters.

PMID:
11443229
[Indexed for MEDLINE]
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