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Semin Neurol. 2001 Jun;21(2):199-207.

Progressive spastic paraparesis: hereditary spastic paraplegia and its relation to primary and amyotrophic lateral sclerosis.

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1
Department of Neurology, University of Michigan and Geriatric Research Education and Care Center, Ann Arbor Veterans Affairs Medical Center, USA.

Abstract

The syndrome of insidiously progressive spastic weakness of both legs occurs in a number of etiologically distinct disorders including hereditary spastic paraplegia (HSP), primary lateral sclerosis (PLS), and sometimes in amyotrophic lateral sclerosis (ALS). This review summarizes the clinical and pathologic relationship between these disorders.

PMID:
11442328
DOI:
10.1055/s-2001-15265
[Indexed for MEDLINE]

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