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Am J Public Health. 2001 Jul;91(7):1126-9.

Immunization and symptoms of atopic disease in children: results from the International Study of Asthma and Allergies in Childhood.

Author information

1
Department of Public Health Sciences, St. George's Hospital Medical School, Cranmer Terrace, London SW17 0RE UK. r.anderson@sghms.ac.uk

Abstract

OBJECTIVES:

This study tested the hypothesis that immunization is related to the prevalence of atopic disease in childhood.

METHODS:

We used data from the International Study of Asthma and Allergies in Childhood to perform an ecologic analysis of national and local immunization rates for tuberculosis, diphtheria and tetanus toxoids and pertussis (DTP), and measles and prevalence of atopic disease symptoms (asthma, allergic rhinoconjunctivitis, and atopic eczema).

RESULTS:

In 13- to 14-year-old children, there were significant negative associations with local birth-year immunization rates for DTP and measles but none with rates for tuberculosis. No associations were found in 6- to 7-year-old children. No associations with national immunization rates were found.

CONCLUSIONS:

International variations in childhood atopic diseases are unlikely to be explained by variations in immunization.

PMID:
11441744
PMCID:
PMC1446713
DOI:
10.2105/ajph.91.7.1126
[Indexed for MEDLINE]
Free PMC Article

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