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Org Lett. 2001 Feb 8;3(3):437-40.

Bogorol A produced in culture by a marine Bacillus sp. reveals a novel template for cationic peptide antibiotics.

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Departments of Chemistry and Earth and Ocean Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z1, Canada.


[figure: see text] Bogorol A (1), a novel peptide antibiotic active against MRSA and VRE, has been isolated from cultures of a marine Bacillus sp. collected in Papua New Guinea. The structure of bogorol A was elucidated by a combination of spectroscopic analyses and chemical degradation. Bogorol A illustrates a new structural template for "cationic peptide antibiotics".

[Indexed for MEDLINE]

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