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Biosci Rep. 2000 Dec;20(6):443-63.

Membrane fusion induced by phospholipase C and sphingomyelinases.

Author information

1
Unidad de Biofisica (CSIC-UPV/EHU), Departamento de Bioquímica, Universidad des País Vasco, Bilbao, Spain. gbpaliza@lg.ehu.es

Abstract

In the past decade lipid vesicle fusion induced by either bacterial PC-preferring phospholipase C, phosphatidylinositol-specific phospholipase C, sphingomyelinase, or a combination of phospholipase C and sphingomyelinase has been demonstrated. In the present paper, the experimental evidence is reviewed, and discussed in terms of the underlying molecular mechanisms of fusion, and of the possible physiological relevance of these findings.

PMID:
11426688
DOI:
10.1023/a:1010450702670
[Indexed for MEDLINE]

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