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Pathol Int. 2001 Jun;51(6):473-5.

Absence of BAT-26 instability in gastric intestinal metaplasia.

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Department of Pathology, Yamagata University School of Medicine, Yamagata, Japan.


BAT-26 instability, a sensitive marker for the high-frequency microsatellite instability (MSI-H) phenotype, was analyzed in samples of gastric cancer and in adjacent intestinal metaplastic mucosae. Although all MSI-H gastric cancer samples showed BAT-26 instability, as assessed using 12 dinucleotide microsatellite markers, BAT-26 instability was not found in the adjacent intestinal metaplastic mucosa in any of the samples.

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