Format

Send to

Choose Destination
J Nat Prod. 2001 Jun;64(6):842-4.

Steroidal alkaloids from the leaves of Sarcococca coriacea of Nepalese origin.

Author information

1
Central Department of Chemistry, Tribhuvan University, Kirtipur, Kathmandu, Nepal.

Abstract

Two new steroidal alkaloids, (-)-vaganine D (1) [(20S)-20-(N,N-dimethylamino)-3 beta-(senecioylamino)-5 alpha-pregn-16-en-4 beta-yl acetate], and (+)-nepapakistamine A (2) [(20S)-20-(N-methylamino)-3 beta-(tigloylamino)-5 alpha-pregn-16-en-2 beta,4 beta-diacetate], were isolated from the leaves of Sarcococca coriacea. Their structures were elucidated on the basis of their spectral properties. Compounds 1 and 2 were found to be cholinesterase inhibitors.

PMID:
11421762
DOI:
10.1021/np000466v
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Chemical Society
Loading ...
Support Center